Among the foremost members of the emerging Cambodian contemporary art scene, Leang Seckon was born in Prey Veng province, Cambodia, in the early 1970s at the onset of the American bombings of Indochina and grew up during the rise of the brutal Khmer Rouge regime.

As art historian Dr. Peter D. Sharrock pointed out, "his paintings and collages attest to a magnificent, ancient sensibility that has survived the vicissitudes and periodic nightmares of Cambodian history. His draughtsmanship and technical innovation articulate the living presence of the artistic gift that produced the mastery of form in stone and bronze which graced the efflorescence of Angkor a thousand years  ago".

A 2002 graduate of the Royal Academy of Fine Arts, Phnom Penh, his works have appeared as illustrations throughout Cambodia and across the world . Notable exhibitions include the artist’s participation in the 2012 Shanghai Biennale, and the 8th Asia Pacific Triennial of Contemporary Art (APT8) held at the Queensland Art Gallery and Gallery of Modern Art in Brisbane, Australia, in 2015, 4th Fukuoka Asian Art Triennale in Japan in 2009, the ASEAN New Zero Contemporary Art Exchange, Yangon, Myanmar, also in 2009, and his Rubbish Project (2008) a public project in Phnom Penh. He has exhibited widely in his home country as well throughout Asia.